Endocrine Abstracts

IntroductionDiabetes mellitus (DM) is a global health issue. Sri Lanka has the second highest diabetes prevalence at 20–79 years in South-East-Asia (1). Diabetic-radiculoplexus-neuropathy is a rare entity causing significant disability, also known as diabetic amyotrophy and Bruns-Garland syndrome, occurring due to immune mediated microvasculitis (2). Although Diabetic-lumbo-sacral-radiculoplexes-neuropathy (DLRPN) is well described, Diabetic-cervica...

BackgroundCushing’s syndrome (CS) occurs due to cortisol overproduction. Endogenous hypercortisolemia can be secondary to Adrenocorticotropic hormone (ACTH) dependent as well as independent causes (1). Early identification and prompt definitive management is crucial to minimize mortality. Successful management of CS becomes extremely challenging due to multiple associated complications, especially the thrombotic events which are even more prominent ...

Introduction: Fluid and sodium disorders are a relatively frequent occurrence after sellar/supra-sellar surgeries. National Hospital of Sri Lanka (NHSL) is the main tertiary care centre in Sri Lanka, conducting regular pituitary surgeries. Methods: A prospective cross-sectional study was conducted in all adults (above 15-years) undergoing pituitary-related surgeries in NHSL over 18 months from September 2019. The relationship between demographic factors,...

Introduction: Primary hyperparathyroidism is a common endocrine disorder, surgery is curative. Patients with severe hypercalcemia receive cinacalcet or intravenous bisphosphonates as bridging. Intra-operative-parathyroid-hormone (IOPTH) measurement improves surgical accuracy. Bisphosphonates may increase PTH, while cinacalcet reduces it. The main aim was to assess the effect of zoledronate and cinacalcet on IOPTH.Method: Patients over 15-yo who underwent...

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disorder. Aim of this audit was to assess clinical, biochemical parameters, localisation modalities and outcome in patients undergoing parathyroidectomy at University College London Hospital (UCLH).Methods: We audited all patients aged 15-years or above, undergoing parathyroidectomy, from 01-02-2018 to 31-12-2021 at UCLH via retrospective data collectio...

Introduction: For clinically relevant sellar masses, early identification and effective endocrine & surgical management is the key. National Hospital of Sri Lanka (NHSL), which is the largest tertiary care centre in Sri Lanka, manages a wide variety of patients with sellar/supra-sellar pathologies, regularly conducting pituitary related surgeries. The aim of the current study was to determine epidemiological and clinical characteristics as well as immediate post-operative ...